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Anti-reflux surgery (fundoplication)

Anti-reflux surgery is a procedure for treating gastroesophageal reflux disease, or GERD. GERD results when acid refluxes from the stomach into the esophagus. Because the esophagus does not have a mucus lining like the stomach, it can become irritated by the acid.

GERD is normally prevented by a functional muscular valve at the junction of the esophagus and stomach, called the lower esophageal sphincter (LES).

  • Most of the time, this sphincter is contracted to close off the esophagus from the stomach, thus acting as a barrier. In patients with GERD, the sphincter is either weak, relaxes inappropriately, or is forced open by a hiatal hernia.
  • GERD causes inflammation, heartburn and other serious complications, such as scarring and narrowing of the esophagus.
  • During an anti-reflux surgical procedure, the part of the stomach closest to the esophagus is sewn around the lower end of the esophagus.
  • This procedure increases the pressure at the lower end of the esophagus to strengthen the valve function and reduce acid reflux.

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Clinical Trials: Anti-reflux surgery (fundoplication)

ÂÜÀòÉç research scientists make medicine better every day. They discover new ways to help people by running clinical trials. When you join a clinical trial, you can get advanced medical care. Sometimes years before it's available everywhere. You can also help make medicine better for everyone else. If you'd like to learn more about clinical trials, visit our clinical trials page. Or click one of the links below:

View all anti-reflux surgery (fundoplication) studies